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Article

The Impact of Gut Microbiota on Chronic Obstructive Pulmonary Disease: A Dual-Sample Mendelian Randomization Study.

International journal of chronic obstructive pulmonary disease - 1 Jan 2025

Niu Na, Zhao Jian, Li Haoxiang, Miao Yongen, Chen Futao, Liu Junyong, Cao Limin, Ji Tuo, Gao Feng, Xie Shuanshuan, Zhang Yunfeng

Abstract excerpt

Background: Chronic Obstructive Pulmonary Disease (COPD) is a major cause of global mortality and disability. Previous research suggests a relationship between gut microbiota and COPD, yet the causal link remains unclear. Hence, we conducted a dual-sample Mendelian randomization study to elucidate the impact of gut microbiota on COPD. Methods: We utilized single-nucleotide polymorphisms (SNPs) as instrumental...

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Identifiers

PMID: 40547287
DOI: 10.2147/COPD.S511383
PMCID: PMC12182233

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