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Article

Associations Between Myopia and Brain Volumes: An Observational and Genetic Analysis.

Investigative ophthalmology & visual science - 2 Jun 2025

Wei Zhang Selena, Guo Jingze, Chen Yanxian, Liu Jiahao, Huang Yu, Shang Xianwen, He Mingguang

Abstract excerpt

Purpose: To examine phenotypic and genetic associations between myopia and various brain volumes using the UK Biobank database. Methods: After 1:1 propensity score matching (PSM) between participants with myopia and healthy controls, the relationship between myopia and brain volumes was examined using general linear regression, with adjustments for covariates including age, sex, ethnicity, Townsend Deprivation...

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Identifiers

PMID: 40530922
DOI: 10.1167/iovs.66.6.57
PMCID: PMC12180605

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