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IFN-γ gene polymorphisms +874 T/A and +2109 A/G are associated with the serofast state after early syphilis treatment: a prospective observational study

2 Jun 2025

Abstract excerpt

Background: , as well as its potential failure and the occurrence of the serofast state, depends on the Th1 cellular response, including cytokines such as IFN-γ. The aim of this prospective observational study was to investigate the impact of IFN-γ gene polymorphisms on the occurrence of the serofast state. Materials and methods: A cohort of 97 patients with early syphilis (73.2% secondary syphilis, 26.8% early...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 40529360
DOI: 10.3389/fimmu.2025.1602527

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