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Article

The impact of adult and lifelong hypoxia on ventricle phenotype in zebrafish (Danio rerio).

American journal of physiology. Regulatory, integrative and comparative physiology - 1 Jul 2025

Smith Brandt, Martinez-Bautista Gil, Williams Steven, Burggren Warren W, Crossley Dane A

Abstract excerpt

Hypoxia occurs naturally in a wide range of aquatic ecosystems. However, the physiological and morphological effects of prolonged hypoxia on organ systems remain poorly understood, especially in the cardiovascular system of fishes. We assessed the contractile force of isolated hearts from adult zebrafish from control conditions (Po2 = 21 kPa), from adults after a 4-wk exposure to hypoxia (Po2 = 10 kPa), or adults...

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Identifiers

PMID: 40514196
DOI: 10.1152/ajpregu.00033.2025
PMCID: PMC12373154

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