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Article

Epigenetic clocks as mediators of health behaviors and mortality in middle-aged and older adults

11 Jun 2025

Abstract excerpt

BACKGROUND: The impact of healthy lifestyles on epigenetic age acceleration (EAA) and mortality in middle-aged/ senior populations remains unclear. This study investigates associations between lifestyle factors, EAA biomarkers, and mortality risk. METHOD: The 2532 adults of 50 years or older that registered in NHANES between 1999-2002.This study evaluated compares first- to third-generation epigenetic clocks...

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PMID: 40505553
DOI: 10.1016/j.jnha.2025.100602

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