Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Copy Number Variant Architecture of Child Psychopathology and Cognitive Development in the ABCD Study.

The American journal of psychiatry - 1 Aug 2025

Sha Zhiqiang, Sun Kevin Y, Jung Benjamin, Barzilay Ran, Moore Tyler M, Almasy Laura, Forsyth Jennifer K, Prem Smrithi, Gandal Michael J, Seidlitz Jakob, Glessner Joseph T, Alexander-Bloch Aaron F

Abstract excerpt

OBJECTIVE: Late childhood is a crucial period for individuals with psychiatric disorders. While common single-nucleotide polymorphisms explain a large proportion of inherited risk, structural variations including copy number variants (CNVs) play a significant role in the genetic architecture of neurodevelopmental disorders. The relevance of CNVs to child psychopathology and cognitive function in the general...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adolescent
Share to Child

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cognition

Share to DNA Copy Number Variations

Share to Mental Disorders

Share to Neurodevelopmental Disorders

Share to Phenotype

Share to Psychopathology

Source

Open in PubMed Open full text

Identifiers

PMID: 40495526
DOI: 10.1176/appi.ajp.20240445
PMCID: PMC12318608

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Copy Number Variant Architecture of Child Psychopathology and Cognitive Development in the ABCD Study.PMID 40495526Read ↗

The copy number variant architecture of psychopathology and cognitive development in the ABCD<sup>®</sup>studySemantic proximity Read ↗

Gene copy number variation in pediatric mental illness in a general populationSemantic proximity Read ↗

Association of copy number variation across the genome with neuropsychiatric traits in the general population.Semantic proximity Read ↗

Gene copy number variation and pediatric mental health/neurodevelopment in a general population.Semantic proximity Read ↗

Clinical and cognitive characteristics of children with attention-deficit hyperactivity disorder, with and without copy number variants.Semantic proximity Read ↗

Genotype-phenotype relationships in children with copy number variants associated with high neuropsychiatric risk: Findings from the Intellectual Disability & Mental Health: Assessing the Genomic Impact on Neurodevelopment (IMAGINE-ID) studySemantic proximity Read ↗

Developmental psychopathology: the role of structural variation in the genome.Semantic proximity Read ↗

Genomic copy number variation in disorders of cognitive development.Semantic proximity Read ↗

Rare CNVs and phenome-wide profiling: a tale of brain-structural divergence and phenotypical convergenceSemantic proximity Read ↗

CNVs: harbingers of a rare variant revolution in psychiatric genetics.Semantic proximity Read ↗

A copy number variation morbidity map of developmental delay.Semantic proximity Read ↗

High-effect gene-coding variants impact cognition, mental well-being, and neighborhood safety substrates in brain morphologySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.