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Article

Role of exosomes in transforming growth factor-β-mediated cancer cell plasticity and drug resistance

5 Jun 2025

Abstract excerpt

Transforming growth factor-β (TGF-β) is a multifunctional molecule with a dual role in carcinogenesis. Recent studies have demonstrated its various effects on cancer-related processes. However, the identification of TGF-β and TGF-β signaling pathway regulators in extracellular vesicles (EVs) appears promising for targeting them to control cancer progression associated with drug resistance. Exosomal TGF-β has been...

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PMID: 40486962
DOI: 10.37349/etat.2025.1002322

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