Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Assessment of CDKN2A homozygous and heterozygous deletions in gliomas across multiple detection platforms

5 Jun 2025

Abstract excerpt

Accurately identification of cyclin-dependent kinase inhibitor 2A (CDKN2A) status is of paramount important, as it has been reported as an unfavorable prognostic biomarker in diffuse gliomas, both IDH-mutant and IDH-wild type. Various methods are available for identifying CDKN2A deletion, with fluorescent in situ hybridization (FISH) being the most used. However, there is currently no established threshold for...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Genomics and Diagnostics
Share to Glioma Diagnosis and Treatment
Share to Radiomics and Machine Learning in Medical Imaging

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 40474207
DOI: 10.1186/s12885-025-14266-x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Assessment of CDKN2A homozygous and heterozygous deletions in gliomas across multiple detection platformsPMID 40474207Read ↗

Evaluation of MTAP and p16 immunohistochemical deficiency as surrogate marker for CDKN2A/B homozygous deletion in gliomas.Semantic proximity Read ↗

Reliability assessment of methylthioadenosine phosphorylase immunohistochemistry as a surrogate biomarker for CDKN2A homozygous deletion in adult-type IDH-mutant diffuse gliomasSemantic proximity Read ↗

Clinical Utility of Assessing CDKN2A Status in Recurrent AstrocytomasSemantic proximity Read ↗

IDH1/2 mutation detection in gliomas.Semantic proximity Read ↗

Utility of methylthioadenosine phosphorylase immunohistochemical deficiency as a surrogate for CDKN2A homozygous deletion in the assessment of adult-type infiltrating astrocytoma.Semantic proximity Read ↗

CDKN2A/B Homozygous Deletions in Astrocytomas: A Literature ReviewSemantic proximity Read ↗

p16 Immunohistochemical Expression as a Surrogate Assessment of CDKN2A Alteration in Gliomas Leading to Prognostic SignificancesSemantic proximity Read ↗

Targeted Next-Generation Sequencing in Molecular Subtyping of Lower-Grade Diffuse Gliomas: Application of the World Health Organization's 2016 Revised Criteria for Central Nervous System Tumors.Semantic proximity Read ↗

A Custom DNA-Based NGS Panel for the Molecular Characterization of Patients With Diffuse Gliomas: Diagnostic and Therapeutic ApplicationsSemantic proximity Read ↗

Comprehensive clinical assays for molecular diagnostics of gliomas: the current state and future prospectsSemantic proximity Read ↗

Comparison of Fluorescence In Situ Hybridization, Next-Generation Sequencing, and DNA Methylation Microarray for Copy Number Variation Assessment in GliomasSemantic proximity Read ↗

[Methylthioadenosine phosphorylase and p16 as surrogate diagnostic markers for CDKN2A homozygous deletion in brain tumors].Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.