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circFAM134B is a key factor regulating reticulophagy-mediated ferroptosis in hepatocellular carcinoma

21 Aug 2023

Abstract excerpt

Ferroptosis is an important mode of regulated cell death (RCD). Its inhibition is closely related to therapeutic resistance and poor prognosis in hepatocellular carcinoma (HCC). Previous reports have demonstrated ferroptosis as a biological process highly dependent on selective autophagy, such as ferritinophagy, lipophagy, and clockophagy. Our study also revealed a role for ER-phagy-mediated ferroptosis in HCC...

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PMID: 37603831
DOI: 10.1080/15384101.2023.2249302

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