Genetic analysis of flagellar-mediated surface sensing by Pseudomonas aeruginosa PA14.

Abstract excerpt

Surface sensing is a key aspect of the early stage of biofilm formation. For Pseudomonas aeruginosa PA14, the type IV pili (T4P), the T4P alignment complex, and PilY1 were shown to play a key role in c-di-GMP signaling upon surface contact. The role of the flagellar machinery in surface sensing is less well understood for P. aeruginosa. Here, we show, consistent with findings from other groups, that a mutation in...

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