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Article

Generating synthetic electronic health record data: a methodological scoping review with benchmarking on phenotype data and open-source software.

Journal of the American Medical Informatics Association : JAMIA - 1 Jul 2025

Chen Xingran, Wu Zhenke, Shi Xu, Cho Hyunghoon, Mukherjee Bhramar

Abstract excerpt

OBJECTIVES: To conduct a scoping review (ScR) of existing approaches for synthetic Electronic Health Records (EHR) data generation, to benchmark major methods, and to provide an open-source software and offer recommendations for practitioners. MATERIALS AND METHODS: We search three academic databases for our scoping review. Methods are benchmarked on open-source EHR datasets, Medical Information Mart for...

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PMID: 40460023
DOI: 10.1093/jamia/ocaf082
PMCID: PMC12203555

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