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Article

OMIP-115: High-Dimensional Phenotypic Characterization of Human Natural Killer Cells for Therapeutic Use.

Cytometry. Part A : the journal of the International Society for Analytical Cytology - 1 Jun 2025

Christensen Emil Birch, Schaefer Moritz, Barnkob Mike Bogetofte, Nielsen Christian, Barington Torben

Abstract excerpt

This 29-color flow cytometry panel was developed and optimized for in-depth characterization of human peripheral blood NK cells for preclinical development and monitoring of NK cell therapies. The panel includes markers associated with NK cell differentiation, cytotoxicity, tissue residency, as well as NK cell dysfunction. Panel optimization was performed on freshly isolated and ex vivo activated NK cells...

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Identifiers

PMID: 40452362
DOI: 10.1002/cyto.a.24941

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