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Article

Exosome-derived SLC12A2-DT promotes macrophage M2 polarization-mediated hepatocellular carcinoma progression

29 May 2025

Abstract excerpt

BACKGROUND: Previous scholarly research highlights the indispensable roles of tumor-associated macrophages (TAMs) and exosomes in the progression of hepatocellular carcinoma (HCC). However, the nuanced molecular mechanisms by which tumor-derived exosomal lncRNAs interact with TAMs to modulate macrophage polarization and HCC proliferation remain largely obscure. METHOD: Clinical specimens were subjected to...

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PMID: 40446695
DOI: 10.1016/j.intimp.2025.114955

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