Article
Fusion of Molecular and Mechanical Phenotypes Enables High-Purity and Low-Loss Reacquisition of Viable CTCs for Transcriptome Analysis.
Analytical chemistry - 10 Jun 2025
Si Haibin, Xu Qing, Sun Yan, Du Dexin, Wang Yiguo, Li Simin, Li Lu, Tang Bo
Abstract excerpt
The high-purity and low-loss reacquisition of viable circulating tumor cells (CTCs) is crucial for enabling downstream omics analysis of CTCs and currently represents key challenges limiting their application in clinical diagnosis and pathological research. Given the limitations of traditional methods that rely solely on a molecular or mechanical phenotype for CTCs acquisition, this study introduces an innovative...
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