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The mechanism of ECT1/E6E7 cervical intraepithelial neoplasia cells regulated by Acinetobacter lwoffii through circ-LDHA/HMGB1

26 May 2025

Abstract excerpt

BACKGROUND: To investigate the mechanism by which Acinetobacter lwoffii-induced circ-LDHA/HMGB1 activation regulates the ability of ECT1/E6E7 cells to promote cervical intraepithelial neoplasia (CIN). METHODS: After establishing a co-culture model of Acinetobacter lwoffii and ECT1/E6E7 cells, the proliferation, migration and apoptosis of ECT1/E6E7 cells were detected by CCK8, transwell and flow cytometry assays....

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PMID: 40414884
DOI: 10.1186/s12866-025-04043-y

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