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Characterization of extracellular vesicle-associated DNA and proteins derived from organotropic metastatic breast cancer cells

23 May 2025

Abstract excerpt

BACKGROUND: While primary breast cancer (BC) is often effectively managed, metastasis remains the primary cause of BC-related fatalities. Gaps remain in our understanding of the mechanisms regulating cancer cell organotropism with predilection to specific organs. Unraveling mediators of site-specific metastasis could enhance early detection and enable more tailored interventions. Liquid biopsy represents an...

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PMID: 40410902
DOI: 10.1186/s13046-025-03418-3

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