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Death-ision: the link between cellular resilience and cancer resistance to treatments

15 May 2025

Abstract excerpt

One of the key challenges in defeating advanced tumors is the ability of cancer cells to evade the selective pressure imposed by chemotherapy, targeted therapies, immunotherapy and cellular therapies. Both genetic and epigenetic alterations contribute to the development of resistance, allowing cancer cells to survive initially effective treatments. In this narration, we explore how genetic and epigenetic...

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PMID: 40375296
DOI: 10.1186/s12943-025-02339-1

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