Uncommon phenotypes of BCR::ABL1-positive chronic myelogenous leukemia.

Abstract excerpt

BCR::ABL1-positive chronic myelogenous leukemia (CML) presents with a typical phenotype in over 95% of cases. These phenotypical cases are associated with a p210 oncoprotein (M-bcr genotype). In these cases, the consideration of CML is high on the list of differential diagnoses and appropriate genetic studies to confirm the BCR::ABL1 oncogene are de rigueur. The elevated white cell count, dominant granulocytes,...

Topics

• Humans
• Leukemia, Myelogenous, Chronic, BCR-ABL Positive
• Fusion Proteins, bcr-abl
• Phenotype
• Male
• Female
• Proto-Oncogene Proteins c-bcr