Article
A decade of genomic and phenotypic adaptation of carbapenem-resistant Acinetobacter baumannii.
Frontiers in cellular and infection microbiology - 1 Jan 2025
Tagueha Astri D, D'Agostini Cartesio, Scribano Daniela, Fiorilla Carlotta, Limongi Dolores, Fillo Silvia, Corrent Luca, Lipari Martina, Lista Florigio, Nencioni Lucia, Palamara Anna Teresa, Ambrosi Cecilia
Abstract excerpt
Introduction: Acinetobacter baumannii exhibits high genomic plasticity, enabling it to acquire virulence factors and antibiotic resistance (AR). Understanding its evolutionary adaptations is crucial for developing effective therapeutic strategies. Methods: Thirty clinical isolates collected from two distinct time periods, defined as older (2010-2013), and recent (2022-2023),- were compared phenotypically...
Read the complete abstract on PubMedTopics
- Acinetobacter baumannii
- Humans
- Biofilms
- Virulence Factors
- Acinetobacter Infections