Genomic characterization of carbapenem-resistant Acinetobacter baumannii from a specialized orthopaedic hospital in Southeast China, with phenotypic analysis of biofilm formation.

doi:10.3389/fcimb.2026.1904047

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Genomic characterization of carbapenem-resistant Acinetobacter baumannii from a specialized orthopaedic hospital in Southeast China, with phenotypic analysis of biofilm formation.

Frontiers in cellular and infection microbiology - 1 Jan 2026

Shi Tengfei, Xu Shaohan, Zheng Xuexin, Shi Weiqiang, Zhang Rui, Chen Hong, Chen Tengyi, Chen Huiyu

Abstract excerpt

Background: Carbapenem-resistant Acinetobacter baumannii (CRAB) is a major threat to hospitalised patients, particularly in intensive care units and orthopaedic wards where implant-associated infections are common. However, the genomic and biofilm characteristics of CRAB in orthopaedic specialty hospitals remain poorly understood. Methods: A total of 97 non-duplicate CRAB isolates collected between 2024 and 2025...

Topics

Biofilms
Acinetobacter baumannii
China
Humans
Anti-Bacterial Agents
Carbapenems
Microbial Sensitivity Tests
Multilocus Sequence Typing
Phylogeny
Acinetobacter Infections

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Whole Genome Sequencing

Genome, Bacterial

Phenotype

Polymorphism, Single Nucleotide

beta-Lactamases

Drug Resistance, Multiple, Bacterial

Bacterial Proteins

Hospitals

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Identifiers

PMID: 42568602
DOI: 10.3389/fcimb.2026.1904047
PMCID: PMC13447295

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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