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Integration of Digital Phenotyping and Genomics for Dry Eye Disease: Protocol for a Prospective Cohort Study.

JMIR research protocols - 12 May 2025

Nagino Ken, Akasaki Yasutsugu, Fuse Nobuo, Ogishima Soichi, Shimizu Atsushi, Uruno Akira, Sutoh Yoichi, Otsuka-Yamasaki Yayoi, Nagami Fuji, Seita Jun, Nakamura Tomohiro, Nagaie Satoshi, Taira Makiko, Kobayashi Tomoko, Shimizu Ritsuko, Hozawa Atsushi, Kuriyama Shinichi, Eguchi Atsuko, Midorikawa-Inomata Akie, Nakamura Masahiro, Murakami Akira, Nakao Shintaro, Inomata Takenori

Abstract excerpt

BACKGROUND: Dry eye disease (DED) is a common ocular condition with diverse and heterogeneous symptoms. Current treatment standards of DED include the post facto management of associated symptoms through topical eye drops. However, there is a need for predictive, preventive, personalized, and participatory medicine. The DryEyeRhythm mobile health app enables real-time data collection on environmental, lifestyle,...

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PMID: 40354653
DOI: 10.2196/67862
PMCID: PMC12107206

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