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Autophagy in cancer and protein conformational disorders

8 May 2025

Abstract excerpt

Autophagy is a catabolic process by which cells maintain cellular homeostasis through the degradation of dysfunctional cytoplasmic components, such as toxic misfolded proteins and damaged organelles, within the lysosome. It is a multistep process that is tightly regulated by nutrient, energy, and stress-sensing mechanisms. Autophagy plays a pivotal role in various biological processes, including protein and...

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PMID: 40342093
DOI: 10.1002/1873-3468.70061

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