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Article

Assessment of ghrelin serum level and gene polymorphism as a risk factor in progression of chronic viral hepatitis.

Scientific reports - 8 May 2025

Kamel Lamiaa Mahmoud, Shawky Nagwa Mohamed, Jouda Amal A, Ibrahim Amany Mohamed, Mahboub Heba H, Mohammed Sherif Y

Abstract excerpt

Hepatocellular carcinoma (HCC) is a significant health concern, ranking as the fourth most common cancer in Egypt and the sixth globally. Research has identified over 300 single nucleotide polymorphisms (SNPs) in the ghrelin gene, with four of these SNPs being associated with pathogenicity. The current work is a pioneer attempt to evaluate the role of Ghrelin gene polymorphism as a risk factor for progression of...

Read the complete abstract on PubMed

Topics

Humans
Ghrelin
Male
Female
Polymorphism, Single Nucleotide
Middle Aged

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Disease Progression

Risk Factors

Carcinoma, Hepatocellular

Liver Cirrhosis

Liver Neoplasms

Adult

Genetic Predisposition to Disease

Case-Control Studies

Egypt

Genotype

Hepatitis B, Chronic

Source

Open in PubMed Open full text

Identifiers

PMID: 40341735
DOI: 10.1038/s41598-025-99037-1
PMCID: PMC12062323

Provenance

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