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The Y58D mutation in rpsJ gene is correlated with tigecycline and eravacycline combined resistance in ST80 vancomycin-resistant Enterococcus faecium isolates.

Journal of global antimicrobial resistance - 1 Jun 2025

Valzano Felice, Beccia Elisa, La Bella Gianfranco, Marangi Marianna, Arena Fabio

Abstract excerpt

OBJECTIVES: To describe the phenotypic and genetic features of vancomycin-resistant Enterococci (VRE) isolates exhibiting resistance to tetracycline (TET), tigecycline (TGC), and eravacycline (ERV). METHODS: Between December 2023 and September 2024, 32 VRE were collected from clinical samples at the Policlinico Foggia, Italy. Bacterial identification was carried out by matrix-assisted laser desorption...

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Drug Resistance, Multiple, Bacterial
Enterococcus faecium
Gram-Positive Bacterial Infections
Multilocus Sequence Typing
Ribosomal Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Vancomycin-Resistant Enterococci

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PMID: 40334841
DOI: 10.1016/j.jgar.2025.04.028

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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