Gut-thyroid axis: investigating the causality between the gut microbiota and autoimmune thyroid disease based on a Mendelian randomization study

Abstract excerpt

INTRODUCTION: Current studies have identified a close connection between the gut microbiota (GM) and autoimmune thyroid disease (AITD), indicating that the dysregulation of the GM could play a crucial bridging role in AITD. However, the causality between them has not been definitively defined. MATERIAL AND METHODS: We utilized the summary statistics of GM from the largest available meta-analysis of genome-wide...

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