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Identification and Validation of Feature Genes Related to Mitochondrial Dysfunction and Oxidative Stress in Ulcerative Colitis

1 Apr 2025

Abstract excerpt

Background: The roles of mitochondrial dysfunction (MD) and oxidative stress (OS) in the pathogenesis of ulcerative colitis (UC) have received increasing attention. Given their close association, it is crucial to clarify the molecular characteristics and biological functions of MD and OS-related genes in UC. Methods: Gene expression profiles, mitochondrial-related genes, and OS-related genes were obtained from...

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PMID: 40331161
DOI: 10.2147/jir.s506851

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