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Article

Phenotyping of Mitral Valve Prolapse Without Severe Mitral Regurgitation Using Electrocardiographic and Echocardiographic Data.

JACC. Clinical electrophysiology - 1 Oct 2025

Tastet Lionel, Ansari Minhaj U, Barrios Joshua P, Cristin Luca, Jhawar Rohit, Rich Amy, Bibby Dwight, Fang Qizhi, Arya Farzin, Tison Geoffrey H, Delling Francesca N

Abstract excerpt

BACKGROUND: Arrhythmic risk stratification in mitral valve prolapse (MVP) without significant mitral regurgitation (MR) remains elusive. Unsupervised machine learning may reveal phenotypic variation among arrhythmic MVP without severe MR. OBJECTIVES: In this study, the authors hypothesized that hierarchical clustering of echocardiographic and 12-lead electrocardiographic (ECG) parameters alone could identify MVP...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 40673846
DOI: 10.1016/j.jacep.2025.06.001
PMCID: PMC13284840

Genes

MVP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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