Article
Developmental exposure to 1,4-dioxane, a volatile organic compound of emerging concern, induces immediate phenotypic, transcriptomic, and adult-onset neurodevelopmental effects.
Toxicological sciences : an official journal of the Society of Toxicology - 1 Aug 2025
Connell Mackenzie L, Akemann Camille, Wu Chia-Chen, Kintzele Emily, Cavaneau Emma, Gonzalez Gabrielle F, Baker Bridget B, Baker Tracie R
Abstract excerpt
1,4-Dioxane, a synthetic volatile organic compound (VOC), has been found in products including paints, cosmetics, and pesticides as well as food products and drinking water. Contamination in groundwater poses significant environmental and public health risks due to its high mobility and widespread human exposure through vapor intrusion and multiroute exposure pathways. Adverse health effects have been observed as...
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