Article
A cross-sectional observational study of patients with sicca with salivary autoantibodies defines a potential new phenotype of Sjögren's disease.
Annals of the rheumatic diseases - 1 Aug 2025
Tsaliki Martha, Cavett Joshua, Kurien Biji T, Bruxvoort Christina, Lewis Valerie M, Ice John A, Dave Devavrat, Khosravani Sina, Grundahl Kiely, Lessard Christopher J, Rasmussen Astrid, Sivils Kathy L, Farris Amy Darise, Koelsch Kristi A, Scofield Robert Hal
Abstract excerpt
OBJECTIVES: Diagnosis of Sjögren's disease (SjD) consists of clinical examinations that include invasive studies such as lower lip biopsies and blood collection to identify presence of serum autoantibodies. Salivary glands of patients with SjD are sites where antibody-secreting cells accumulate and secrete immunoglobulins. Many patients with dry manifestations who do not meet classification criteria are grouped...
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