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Comprehensive molecular profiling of advanced NSCLC using NGS: Prevalence of druggable mutations and clinical trial opportunities in the ATLAS study

24 Apr 2025

Abstract excerpt

BACKGROUND: In Spain, next-generation sequencing (NGS) is currently available in a limited number of specialized centers and remains inaccessible to a significant proportion of patients. The ATLAS study aims to explore the tumor molecular profile beyond known EGFR mutations and ALK translocations using NGS on tumor biopsy samples. METHODS: Patients with EGFR-sensitizing mutations or ALK translocations were...

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PMID: 40300279
DOI: 10.1016/j.lungcan.2025.108550

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