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Article

Prognostic Value of SOX2 and NANOG Expression in Recurrent Oral Squamous Cell Carcinoma

31 Mar 2025

Abstract excerpt

Background: Recurrent oral squamous cell carcinoma (re-OSCC) poses a serious therapeutic challenge and is linked to poor survival outcomes. SOX2 and NANOG, key transcription factors in cancer stem cell biology, may drive tumor progression and therapy resistance. However, their prognostic value in re-OSCC and their relationship to adjuvant therapy remain unclear. Methods: We retrospectively analyzed a...

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PMID: 40227667
DOI: 10.3390/cancers17071181

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