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Bioinformatic Analysis of Apoptosis-Related Genes in Preeclampsia Using Public Transcriptomic and Single-Cell RNA Sequencing Datasets

1 Apr 2025

Abstract excerpt

Purpose: Apoptosis, which is crucial in preeclampsia (PE), affects trophoblast survival and placental function. We used transcriptomics and single-cell RNA sequencing (scRNA-seq) to explore apoptosis-related genes (ARGs) and their cellular mechanisms as potential PE biomarkers. Patients and Methods: All the data included in this study were sourced from public databases. We used scRNA-seq and differential...

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PMID: 40224388
DOI: 10.2147/jir.s507660

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