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Article

Whole-genomic comparison reveals complex population dynamics and parasitic adaptation of Echinococcus granulosus sensu stricto.

mBio - 14 May 2025

Wu Yao-Dong, Ren Zirui, Li Li, Li Wen-Hui, Zhang Nian-Zhang, Wu Yan-Tao, Dai Guo-Dong, Chen Wei-Gang, Mu Wen-Jie, Wang Shuai, Li Jiandong, Yu Qin, Cai Xue-Peng, Jin Xin, Fu Bao-Quan, Wang Daxi, Jia Wan-Zhong, Yan Hong-Bin

Abstract excerpt

Cystic echinococcosis (CE), caused by Echinococcus granulosus sensu stricto (s.s.), poses a substantial risk to both humans and domestic animals globally. Here, we compared the whole genomes of 111 E. granulosus s.s. samples from China. Genomic variation data revealed frequent cross-fertilization in the hermaphroditic E. granulosus. The G1 and G3 genotypes represent distinct mitochondrial lineages, while showing...

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Identifiers

PMID: 40207926
DOI: 10.1128/mbio.03256-24
PMCID: PMC12077126

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