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Article

Quantification of Drosophila melanogaster Grooming Behavior for Evaluation of Excessive Grooming Phenotypes.

Journal of visualized experiments : JoVE - 21 Mar 2025

Hatfield Theodore, Johnson Seth

Abstract excerpt

Observable changes in stereotyped grooming are applied translationally in model organisms. These changes are representative of pathologies that elicit similar deviations in human behavior; for example, excessive grooming acts as a proxy for obsessive and compulsive behaviors present in conditions like Tourette Syndrome or obsessive-compulsive disorder. The grooming assay presented allows for the evaluation of...

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PMID: 40193305
DOI: 10.3791/67708

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