Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Raffinose-metabolizing bacteria impair radiation-associated hematopoietic recovery via the bile acid/FXR/NF-κB signaling pathway

7 Apr 2025

Abstract excerpt

Radiation-associated hematopoietic recovery (RAHR) is critical for mitigating lethal complications of acute radiation syndrome (ARS), yet therapeutic strategies remain limited. Through integrated multi-omics analysis of a total body irradiation (TBI) mouse model, we identify Bacteroides acidifaciens-dominated gut microbiota as key mediators of RAHR impairment. 16S ribosomal rRNA sequencing revealed TBI-induced...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA Repair Mechanisms
Share to Effects of Radiation Exposure
Share to Genomics, phytochemicals, and oxidative stress

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 40192235
DOI: 10.1080/19490976.2025.2488105

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Raffinose-metabolizing bacteria impair radiation-associated hematopoietic recovery via the bile acid/FXR/NF-κB signaling pathwayPMID 40192235Read ↗

Review: Effect of Gut Microbiota and Its Metabolite SCFAs on Radiation-Induced Intestinal InjurySemantic proximity Read ↗

An Integrated Multi-Omic Approach to Assess Radiation Injury on the Host-Microbiome AxisSemantic proximity Read ↗

MIIST305 mitigates gastrointestinal acute radiation syndrome injury and ameliorates radiation-induced gut microbiome dysbiosisSemantic proximity Read ↗

Multi-omics analyses of radiation survivors identify radioprotective microbes and metabolitesSemantic proximity Read ↗

MIIST305 mitigates gastrointestinal acute radiation syndrome injury and ameliorates radiation-induced gut microbiome dysbiosisSemantic proximity Read ↗

A Review of Radiation-Induced Alterations of Multi-Omic Profiles, Radiation Injury Biomarkers, and CountermeasuresSemantic proximity Read ↗

Roseburia intestinalis sensitizes colorectal cancer to radiotherapy through the butyrate/OR51E1/RALB axisSemantic proximity Read ↗

Effect of low-dose radiation on thyroid function and the gut microbiotaSemantic proximity Read ↗

Bacterial Supplements Attenuate Pelvic Irradiation-Induced Brain Metabolic Disruptions via the Gut-Brain Axis: A Multi-Omics InvestigationSemantic proximity Read ↗

Acute Impacts of Ionizing Radiation Exposure on the Gastrointestinal Tract and Gut Microbiome in MiceSemantic proximity Read ↗

Specific Members of the Gut Microbiota are Reliable Biomarkers of Irradiation Intensity and Lethality in Large Animal Models of Human HealthSemantic proximity Read ↗

Rosmarinic Acid Alleviates Radiation-Induced Pulmonary Fibrosis by Downregulating the tRNA N7-Methylguanosine Modification-Regulated Fibroblast-to-Myofibroblast Transition Through the Exosome PathwaySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.