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Article

Genetic Confounding in the Association Between Traumatic Brain Injury and Mental Disorder or Suicide.

JAMA psychiatry - 1 Jun 2025

Østergaard Søren Dinesen, Mundy Jessica, Hall Alisha Silvia Mercedes, Musliner Katherine L

Abstract excerpt

Importance: Traumatic brain injury is common and occurs across all ages. Observational studies have shown that traumatic brain injury is associated with a wide range of mental disorders and suicide. Whether these associations represent a causal effect is, however, difficult to establish, and confounding by genetic liability for mental disorder may play a substantial role. Objective: To investigate whether...

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Identifiers

PMID: 40172901
DOI: 10.1001/jamapsychiatry.2025.0318
PMCID: PMC11966476

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