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A Phenome-Wide Association Study of Marijuana Use and Circulating Biomarkers in the United States: National Health and Nutrition Examination Survey 2009-2018.

Journal of clinical pharmacology - 1 Sept 2025

Zhang Cancan, Mostofsky Elizabeth, Zhang Hui, Zhang Bo, Lindenberg Julia, Amat Maelys J, Mukamal Kenneth J

Abstract excerpt

This study aimed to assess the associations between recent cannabis use and 49 biochemical biomarkers in a representative sample of American adults, using data from the 2009-2018 National Health and Nutrition Examination Survey. A phenotype-wide association study (PheWAS) was conducted to uncover new biomarkers linked to cannabis use. The analysis included 19,926 adults aged 18-59, with a mean age of 38.93 years...

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PMID: 40167582
DOI: 10.1002/jcph.70022

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