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Article

Investigation of the genetic background of familial hypercholesterolemia in a Turkish cohort and its clinical implications.

Journal of clinical lipidology - 1 Jan 2025

Kındış Erdem, Aygün Sevda, Ertürk Banu, Kabaçam Serkan, Lafcı Naz Güleray, Tokgözoğlu Lale, Alikaşifoğlu Mehmet

Abstract excerpt

OBJECTIVE: Familial hypercholesterolemia (FH) is a genetic disorder characterized by elevated plasma cholesterol and an increased risk of early-onset coronary artery disease (CAD). FH has a complex genetic basis. Advances in molecular genetic techniques have deepened our understanding of FH, which is critical for accurate classification, CAD risk assessment, and optimized treatment strategies. This study aimed to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 40157861
DOI: 10.1016/j.jacl.2025.02.016

Genes

FH
CAD
LDLR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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