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Endoplasmic reticulum stress: an emerging therapeutic target for preeclampsia

28 Mar 2025

Abstract excerpt

Preeclampsia (PE), a common obstetric complication during pregnancy, has a global prevalence of 5-8%, and it is one of the leading causes of adverse maternal and fetal outcomes, which has a lack of effective treatment other than termination of pregnancy. Endoplasmic reticulum stress (ERS) is a self-stress response of cells to alleviate misfolded and unfolded protein aggregation and calcium ion homeostasis...

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PMID: 40156296
DOI: 10.1093/biolre/ioaf071

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