Article
Divergent evolutionary trajectories of influenza B viruses underlie their contemporaneous epidemic activity.
Proceedings of the National Academy of Sciences of the United States of America - 7 Jan 2020
Virk Ramandeep K, Jayakumar Jayanthi, Mendenhall Ian H, Moorthy Mahesh, Lam Pauline, Linster Martin, Lim Julia, Lin Cui, Oon Lynette L E, Lee Hong Kai, Koay Evelyn S C, Vijaykrishna Dhanasekaran, Smith Gavin J D, Su Yvonne C F
Abstract excerpt
Influenza B viruses have circulated in humans for over 80 y, causing a significant disease burden. Two antigenically distinct lineages ("B/Victoria/2/87-like" and "B/Yamagata/16/88-like," termed Victoria and Yamagata) emerged in the 1970s and have cocirculated since 2001. Since 2015 both lineages have shown unusually high levels of epidemic activity, the reasons for which are unclear. By analyzing over 12,000...
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