Genistein improves depression-like behavior in rats by regulating intestinal flora and altering glutamate gene expression

Abstract excerpt

Depression is a mental disorder, and genistein is known to have antidepressant effects, but its mechanism of action is still unclear. Here, the mechanism of genistein improving depression based on gut microbiota was explored using classic behavioral indicators of depression combined with genomic technology. The behavioral evaluation showed that rats gavaged with 20-40 mg/kg genistein showed an increase in body...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Diet and metabolism studies
• Share to Diet, Metabolism, and Disease
• Share to Stress Responses and Cortisol