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Alterations of the Composition and Neurometabolic Profile of Human Gut Microbiota in Major Depressive Disorder

2 Sept 2022

Abstract excerpt

Major depressive disorder (MDD) is among the most prevalent mental disorders worldwide. Factors causing the pathogenesis of MDD include gut microbiota (GM), which interacts with the host through the gut–brain axis. In previous studies of GM in MDD patients, 16S rRNA sequencing was used, which provided information about composition but not about function. In our study, we analyzed whole metagenome sequencing data...

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PMID: 36140263
DOI: 10.3390/biomedicines10092162

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