Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Phenotypic alterations in peripheral blood B Lymphocytes of patients with Alzheimer's Disease

22 Mar 2025

Abstract excerpt

INTRODUCTION: Dysfunction of humoral immunity has been implicated in the pathogenesis of Alzheimer's disease (AD). The distribution of B lymphocyte subsets and their clinical relevance in AD remain unclear. OBJECTIVE: In this study, we aimed to investigate the distribution of peripheral blood B lymphocyte subsets and their relevance with cognition and biomarkers in AD. DESIGN, SETTING, AND PARTICIPANTS: We...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alzheimer's disease research and treatments
Share to Neuroinflammation and Neurodegeneration Mechanisms
Share to Tryptophan and brain disorders

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 40121165
DOI: 10.1016/j.tjpad.2025.100135

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Phenotypic alterations in peripheral blood B Lymphocytes of patients with Alzheimer's DiseasePMID 40121165Read ↗

Peripheral blood lymphocyte phenotypes in Alzheimer and Parkinson's diseases.Semantic proximity Read ↗

Adaptive immune changes associate with clinical progression of Alzheimer’s diseaseSemantic proximity Read ↗

β-Amyloids and Immune Responses Associated with Alzheimer’s DiseaseSemantic proximity Read ↗

Exploratory study on immune phenotypes in Alzheimer's disease and vascular dementia.Semantic proximity Read ↗

Altered T cell reactivity to β-amyloid-related antigens in early Alzheimer’s diseaseSemantic proximity Read ↗

Altered T-cell reactivity in the early stages of Alzheimer's diseaseSemantic proximity Read ↗

Double negative (IgG+IgD-CD27-) B cells are increased in a cohort of moderate-severe Alzheimer's disease patients and show a pro-inflammatory trafficking receptor phenotype.Semantic proximity Read ↗

Association of B cell profile and receptor repertoire with the progression of Alzheimer’s diseaseSemantic proximity Read ↗

Dramatic Shifts in Circulating CD4 but not CD8 T Cell Subsets in Mild Alzheimer's DiseaseSemantic proximity Read ↗

Association of B cell profile and receptor repertoire with the progression of Alzheimer’s diseaseSemantic proximity Read ↗

Terminally differentiated effector memory T cells associate with cognitive and AD-related biomarkers in an aging-based community cohortSemantic proximity Read ↗

A systems immunology analysis of Alzheimer’s disease reveals an age- and environmental exposure-independent disturbance in B cell maturationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.