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The Role and Mechanism of Action of Mitophagy in Various Liver Diseases

26 Aug 2022

Abstract excerpt

Significance: Liver disease is one of the biggest threats to public health, affecting as much as 5.5 million people worldwide. Mitochondrial dysfunction is associated with various acute and chronic liver diseases. Mitophagy, a selective form of autophagy for damaged/excessive mitochondria, plays a key role either in the pathogenesis or in maintaining hepatic homeostasis in response to various liver diseases....

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PMID: 36017629
DOI: 10.1089/ars.2022.0114

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