Article
Lysine lactylation analysis of proteins in the heart of the Kawasaki disease mouse model
6 Mar 2025
Abstract excerpt
Introduction: Kawasaki disease (KD) is a medium-vessel vasculitis predominantly affecting children under 5 years of age and may involve the coronary arteries. Methods: cell wall extracts (CAWS), cardiac tissues were analyzed through integrated lactylomic and proteomic profiling. The lysine lactylation (Kla) results were normalized to the proteomic data. Results: Elevated serum lactate and lactate dehydrogenase...
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