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Article

Polymorphisms in the calcium voltage-gated channel subunit Alpha1 D (CACNA1D) gene are associated with spontaneous preterm birth in Taiwanese women.

Journal of the Formosan Medical Association = Taiwan yi zhi - 1 Mar 2026

Chang Tzu-Yang, Kao Tzu-Hsiang, Kuo Yi-Hsiu, Chen Chia-Yu, Chen Chie-Pein

Abstract excerpt

PURPOSE: Calcium signaling is essential for immune function, myometrial contractions, and hormone secretion, all of which contribute to preterm birth. In this study, we investigated the associations of 3 single-nucleotide polymorphisms (SNPs) in CACNA1D gene, which encodes the Cav1.3 calcium channel, with the risk of spontaneous preterm birth (sPTB). METHODS: A hospital-based case-control study was conducted with...

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Identifiers

PMID: 40113473
DOI: 10.1016/j.jfma.2025.03.010

Genes

CACNA1D

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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