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Article

Effect of prevaccination blood and T-cell phenotypes on antibody responses to a COVID-19 mRNA vaccine.

International immunology - 17 Jun 2025

Hidaka Yu, Jo Norihide, Kikuchi Osamu, Fukahori Masaru, Sawada Takeshi, Shimazu Yutaka, Yamamoto Masaki, Kometani Kohei, Nagao Miki, Nakajima Takako E, Muto Manabu, Morita Satoshi, Hamazaki Yoko

Abstract excerpt

Despite the high effectiveness of the coronavirus disease 2019 (COVID-19) mRNA vaccines, both immunogenicity and reactogenicity show substantial interindividual variability. One key challenge is predicting high and low responders using easily measurable parameters. In this study, we performed multivariate linear regression analysis, which allows adjustment for confounding, to explore independent predictive...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 40110889
DOI: 10.1093/intimm/dxaf013
PMCID: PMC12190804

Genes

CD4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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