Article
New perspectives on Drosophila melanogaster de novo gene origination revealed by investigation of ancient African genetic variation.
Genetics - 8 May 2025
Cridland Julie M, Polston Elizabeth S, Begun David J
Abstract excerpt
De novo genes can be defined as sequences producing evolutionarily derived transcripts that are not homologous to transcripts produced in an ancestor. While they appear to be taxonomically widespread, there is little agreement regarding their abundance, their persistence times in genomes, the population genetic processes responsible for their spread or loss, or their possible functions. In Drosophila...
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