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Genomic and phylogenetic analysis of hypervirulent Klebsiella pneumoniae ST23 in Ireland.

Microbial genomics - 1 Mar 2025

Maguire Mark, DeLappe Niall, Clarke Christina, Touhy Alma, Carlino-MacDonald Ulrike, Hutson Alan, Cormican Martin, Brennan Wendy, Devane Genevieve, Morris Dearbháile, Coughlan Simone C, Miliotis Georgios, Russo Thomas A, Burke Liam P

Abstract excerpt

Hypervirulent Klebsiella pneumoniae (hvKp) has emerged as a pathogen of global concern associated with invasive community-acquired infections. The combination of hypervirulence and carbapenem resistance can result in severe and difficult-to-treat infections. This retrospective study aimed to investigate the spread of hvKp sequence type 23 (ST23) in Ireland and the convergence of hypervirulent (hv) and...

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Identifiers

PMID: 40106330
DOI: 10.1099/mgen.0.001373
PMCID: PMC12452180

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