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Article

Enhanced expression of lncRNA TP73-AS1 predicts adverse phenotypes for cholangiocarcinoma and exerts oncogenic properties in vitro and in vivo.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie - 1 Oct 2018

Yao Yue, Sun Yue, Jiang Yuehong, Qu Lijun, Xu Yi

Abstract excerpt

Cholangiocarcinoma (CCA) is one of the most aggressive malignancies with increasing incidence worldwide. Various evidence documents that abnormally expressed long non-coding RNAs (lncRNAs) play important roles in tumorigenesis and progression. TP73-AS1 is a novel cancer-related lncRNA that contributes to the development of several malignancies. However, its clinical value and potential effects on CCA remains...

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PMID: 29966969
DOI: 10.1016/j.biopha.2018.06.045

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